New Tube Baby Treatments for Polycystic Ovary Patients
Polycystic ovary syndrome brings with it the problem of infertility, especially in women of reproductive age due to the problem of ovulation it creates. These patients are often able to conceive with assisted reproductive techniques. With the in vitro maturation (IVM) technique, which is a more frequently talked-about novelty recently, avoids a number of side effects due to hormone therapy given to patients starting tube baby treatment and improves pregnancy success it is possible to increase.
Polycystic ovary syndrome (PCOS), which is an ovulation disorder disease whose cause is not completely clear, brings infertility problems, especially in women who have problems not being able to ovulate during reproductive age. And these patients are often able to conceive with assisted reproductive techniques. She pointed out that the only problem faced by polycystic ovary patients, which accounted for about 15-20% of the test-tube baby patients, was no difficulty in conceiving naturally. As a result of the hormone therapy used in the patients who started the tube baby treatment, he continued to point out that the development of a large number of eggs from normal caused a number of side effects.
This side effect, defined as “OHSS (overlying hyperstimulation syndrome), is a buildup of fluid in areas outside the body due to some signals released into the blood from eggs that have grown and are over normal. Nausea, vomiting, diarrhea, bloating and fluid buildup in the abdomen, fluid buildup in the lungs, increased blood clotting. In the patient who is faced with a life-threatening situation, this condition may last for several weeks, sometimes even requiring hospitalization and intensive treatment.”
A new perspective for patients with IVM PCOS
About IVM (in vitro maturation) of a recent important innovation, that is, the technique of maturing eggs in the laboratory environment, to avoid this condition that threatens the health of patients;
In the treatment of “Tube baby, drugs are used daily in needle form to develop eggs. In addition, an ultrasound and blood test are performed in 2-3 days and the development of the eggs is monitored. In the newly developed IVM method, the growth of eggs with hormones is done with lower dose drugs, the collection of eggs at earlier periods when egg size occurs slightly. Here, eggs that exist in the woman but are not yet fully mature are collected and mature in environments that are specially developed in laboratories. These eggs are then fertilized with sperm and the normal tube baby process is performed. The developed embryos are placed in the womb with the classical transfer process. Thus, eggs that do not reach dangerous size and number in the body do not contribute to the development of OHSS syndrome
The procedure must be performed in an advanced laboratory environment
The most important disadvantage of IVM method is that pregnancy rates are lower than in classical tube baby treatment, so the procedure should be performed under modern technology laboratory conditions and by experienced embryologists.
PCOS plays a very important role in women's lives
In this extremely important hormonal disease, the development of the egg that needs to be cracked by developing in each menstrual cycle is halved and the liquid sac in which the egg develops, that is, the follicle turns into cysts with a diameter of 3-10 millimeters in the ovarian tissue. Ovarian tissue, when these cysts increase in number, turns into a structure that contains “polycystic”, that is, a large number of cystic formations. This is how the appearance of follicles lined up like pearls form in the ovary, which is the classic finding of polycystic ovary disease. Irregular menstrual bleeding, hair removal, pimples, difficulty conceiving or not staying, increased risk of miscarriage, etc, the symptoms of diabetes and health problems such as an increased risk of developing the disease in the future and an increased risk of uterine cancer play an important role in the life of these women.