Why is preimplantation genetic diagnosis (PGD) performed?

Preimplantation Genetic Diagnosis is a general definition given to the genetic examination of embryos developed after tube baby administration. It is applied for the purpose of separation of embryos with a genetic disease or chromosome disorder before pregnancy occurs. After the embryos are analyzed, the normally determined ones are transferred. There are different methods of PGT (PGD) applications.

Benefits of the PGT method

- Increases the success of tube baby application in appropriate cases.
- Increases the pregnancy rate.
- Reduces the risk of pregnancy resulting in an abortus (low).
- Reduces the necessity of medical termination of pregnancy.
- Reduces the rate of multiple pregnancies.
- Reduces the economic and psychological burdens of repeated failed IVF trials.

situations where PGD should be applied

expectant mothers aged 36 years and over
Couples who have not achieved pregnancy despite the application of two or more tube babies
- couples with recurrent early pregnancy losses (lows) (non-translation surrogacy causes)
- Balanced translocation carrier to couples, couples,
- Familial Mediterranean anemia, Sickle Cell Anemia, Cystic fibrosis, SMA to partners who are at risk for some possible single gene diseases, such as,
Couples who have a child with genetic diseases from previous pregnancies
- Mothers with a history of pregnancy with aneuploidy (with chromosome disorder)
- Severe cases of male infertility and TESE (includes with severe male infertility).

How is the PGT test performed?

 - The reproductive health specialist doctor and genetic counselor clarify whether the patient is eligible for PGD

 - Tube baby treatment is started

 - The egg from the mother is fertilized with sperm obtained from the father

- Biopsy is taken from the resulting embryo

 - Embryos that carry genetic diseases and show chromosomal disorders are destroyed by selection and healthy embryos are transferred to the mother's uterus.